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10 Best Natural Supplements for Depression

by Andreea Laza

Looking for natural supplements for depression? Keep on reading and find what are the best supplements to overcome depression.


As I’ve mentioned in a previous article on home remedies for depression, depression is a condition of the mind that reflects on the body and ultimately on the behavior and lifestyle of the person depressed. Depression can start both ways and it can be cured both ways.

Depression is triggered by negative thought patterns supported by a poor diet that is depleting the body from precious minerals and vitamins.

Natural Supplements for Depression

I know that you can’t see this possible from the place you’re in now, but these natural supplements will help lift your spirit, change your perspective, and ultimately see things differently.

When you change your perspective upon things and see the bigger picture, you’re whole state of being changes.

Remember that the state of creating circumstances, and not the other way around. Focus on the positives, be thankful for the experience of life, and allow your perspective to adjust to the new positive reality that you want to create. In this article, we will further discuss the natural supplements for depression that you can take. These supplements, together with healthy, balanced eating (mostly raw fruits, veggies, legumes, and nuts) will definitely aid you in overcoming depression.

10 Best Natural Supplements for Depression

1. Calcium

10 Best Natural Supplements for Depression - Calcium Seeds

Calcium can easily be depleted from the body when we eat too much dairy, but also when we are stressed. This is why calcium is one of the best natural supplements for depression. Some of the best natural sources of calcium are:

  • green barley
  • sesame seeds
  • soy
  • almonds
  • peanuts
  • spinach
  • nuts
  • oatmeal
  • buckwheat
  • millet
  • turnips
  • sprouts
  • brown rice

2. Magnesium

Together with calcium, magnesium is your best friend when you’re going through a depression or very stressful situation. When you have brittle nails, and frail or falling hair, a good magnesium supplement can really help. You can also find natural sources of magnesium in:

  • sunflower seeds
  • almonds
  • soybeans
  • walnuts
  • seaweed
  • whole wheat flour
  • millet
  • spinach
  • bananas
  • green leafy vegetables
  • avocados
  • wheat germ

3. Vitamin B Complex (B1, B6, B12)

Vitamin B1 is amazing against migraines caused by excessive thinking and depression. This Vitamin helps the brain function properly, it’s good for memory and against panic attacks. Vitamins B6 and B12 are also tremendously important when going through depression. Natural sources of B1 Vitamin are:

  • asparagus
  • brown rice
  • peas
  • new potatoes
  • grapes
  • sunflower seeds

4. Omega 3

The omega-3 polyunsaturated fatty acids have been called “the happy foods” because these fatty acids are the essential constituents of the brain that the body cannot synthesize. Supplementing with Omega-3-rich foods and supplements can help relieve depression, increase cognitive function, and prevent neurodegenerative diseases (Alzheimer’s, Parkinson’s, etc.). Yes, Omega-3 fatty acids are amongst the top natural supplements for depression. The best natural sources of Omega 3 are:

  • salmon
  • herring
  • tuna
  • sardines
  • nuts
  • extra virgin olive oil
  • soybean oil
  • flaxseed oil
  • flaxseeds
  • sunflower seeds

5. Sepia 15 CH

Sepia 15 CH is a powerful homeopathic medicine for depression and one of the most powerful natural supplements for depression. This homeopathic medicine is prepared from the cuttlefish’s ink (Sepia officinalis). Cuttlefish ink is rich in trace elements and amino acids such as calcium and magnesium. Its main constituent is melanin, a gray pigment that has about 3.24% sulfur.

6. Royal Jelly & Pollen

Bee products act as natural supplements for depression because they have the property to inhibit prostaglandins. These are active lipid compounds that are responsible for releasing inflammatory proteins in the body and causing headaches. In order to fight off depression, you can take 1 tsp of pollen a day for a 3-month cure. Couple it with a natural royal jelly for stronger anti-depressant effects, or even better have honey with pollen and royal jelly in it. Continue the cure until you feel the depression symptoms are gone.

7. Ginger

Ginger is great for somatic symptoms of depression, especially for nausea and vomiting. Have 1 cm of grated ginger whenever you feel like vomiting or nauseated. Ginger is also one of the best natural antibiotics out there.

10 Best Natural Supplements for Depression - Ginger

8. Herbal Extracts

Rosemary, basil, and St. John’s wort act as natural mental refreshers and are great natural supplements for depression. You can use natural extracts of these herbs as supplements, or enjoy teas made from these plants. They help soothe the mind, induce relaxation, and reduce stress and anxiety.

9. Ginseng

Ginseng helps to increase serotonin levels naturally and is very beneficial in depression, fatigue, burnout, etc. According to studies, ginseng is not only a powerful anti-depressant, but also a natural anti-inflammatory, which is amazing, given the fact that stress pumps adrenaline, which is corrosive and creates inflammation in the body. Not only the Chinese ginseng (Panax ginseng) is an amazing natural anti-depressant, but also its cousin Siberian ginseng, also known as Eleuthero.

10. Maca

(Lepidium meyenii)

Also known as “Peruvian ginseng”, Maca is a root veggie rich in amino acids, phytonutrients, vitamins, and minerals. A study published in the BMC Complementary and Alternative Medicine in 2016 concluded that maca clearly acts as a general antidepressant. This superfood makes the list of the best natural supplements for depression.

Read Also: 5 Best Natural Supplements for Stress & Anxiety

We really hope that the natural supplements for depression that you’ve found here will truly help you out. Let us know what worked for you best in the comments below. Stay healthy and happy, naturally!

best natural supplements for depression

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